SCHEMBL650340

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL650341	1.00	MAPT (0.45)	MAPTLMNAPTP4A3DAPK3DYRK3
	SCHEMBL651165	0.90	MAPT (0.52)	MAPTLMNAPTP4A3NPSR1RECQL
	SCHEMBL651164	0.90	MAPT (0.52)	MAPTLMNAPTP4A3NPSR1RECQL
	SCHEMBL649993	0.90	RNASEL (0.43)	MAPTLMNAPTP4A3NPSR1RECQL
	SCHEMBL651383	0.90	RNASEL (0.43)	MAPTLMNAPTP4A3NPSR1RECQL
	SCHEMBL653877	0.89	MAPT (0.48)	MAPTLMNAPTP4A3DAPK3DYRK3
	SCHEMBL653878	0.89	MAPT (0.48)	MAPTLMNAPTP4A3DAPK3DYRK3
	SCHEMBL653119	0.88	MAPT (0.52)	MAPTDAPK3DYRK3PIM1CSNK2A1
	SCHEMBL653120	0.88	MAPT (0.52)	MAPTDAPK3DYRK3PIM1CSNK2A1
	SCHEMBL10176547	0.86	MAPT (0.47)	MAPTLMNAPTP4A3DAPK3DYRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.