Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503531 | 1.00 | PYGL (0.46) | PYGLPSMB5LNPEPTACR3CDK2 | |
| SCHEMBL3971232 | 0.93 | PYGL (0.47) | PYGLPSMB5LNPEPTACR3CDK2 | |
| SCHEMBL3979419 | 0.93 | PYGL (0.47) | PYGLPSMB5LNPEPTACR3CDK2 | |
| SCHEMBL3974514 | 0.89 | PYGL (0.50) | PYGLLNPEPTACR3CDK2TSHR | |
| SCHEMBL3974510 | 0.89 | PYGL (0.50) | PYGLLNPEPTACR3CDK2TSHR | |
| SCHEMBL5926278 | 0.86 | PYGL (0.55) | PYGLPSMB5LNPEPTACR3CDK2 | |
| SCHEMBL3991444 | 0.84 | ITGA4 (0.48) | — | |
| SCHEMBL5927011 | 0.84 | ITGA4 (0.48) | — | |
| SCHEMBL3998558 | 0.83 | ABCG2 (0.48) | LNPEPTACR3TSHRKDM4EALDH1A1 | |
| SCHEMBL3996954 | 0.83 | ABCG2 (0.48) | LNPEPTACR3TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014532-A1 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | disclosed |