Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923156 | 0.93 | ADRB2 (0.46) | ADRB2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4386833 | 0.88 | ADRB2 (0.65) | ADRB2 | |
| SCHEMBL6508746 | 0.87 | ADRB2 (0.52) | ADRB2NPC1RAB9APRMT5WDR77 | |
| SCHEMBL6533340 | 0.86 | ADRB2 (0.49) | ADRB2 | |
| SCHEMBL6529084 | 0.86 | ADRB2 (0.51) | ADRB2KMT2AMEN1 | |
| SCHEMBL6508632 | 0.84 | ADRB2 (0.49) | ADRB2 | |
| SCHEMBL6506995 | 0.84 | ADRB2 (0.47) | ADRB2 | |
| SCHEMBL2452475 | 0.83 | ADRB2 (0.63) | ADRB2 | |
| SCHEMBL2452118 | 0.83 | ADRB2 (0.63) | ADRB2 | |
| SCHEMBL6509325 | 0.83 | ADRB2 (0.48) | ADRB2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |