Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506995 | 0.97 | ADRB2 (0.47) | ADRB2ADRB1ADRB3POLB | |
| SCHEMBL6508632 | 0.92 | ADRB2 (0.49) | ADRB2ADRB1POLB | |
| SCHEMBL3913331 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3POLB | |
| SCHEMBL6529084 | 0.92 | ADRB2 (0.51) | ADRB2ADRB1POLB | |
| SCHEMBL6509325 | 0.91 | ADRB2 (0.48) | ADRB2ADRB1POLB | |
| SCHEMBL3915484 | 0.90 | ADRB2 (0.45) | ADRB2ADRB1ADRB3POLB | |
| SCHEMBL6530357 | 0.89 | ADRB2 (0.47) | ADRB2ADRB1POLB | |
| SCHEMBL6503586 | 0.86 | ADRB2 (0.48) | ADRB2 | |
| SCHEMBL6508454 | 0.85 | ADRB2 (0.47) | ADRB2ADRB1 | |
| SCHEMBL6507412 | 0.85 | KDM4E (0.49) | ADRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |