Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13296102 | 0.80 | GPR3 (0.55) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28479943 | 0.76 | MAPT (0.52) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28383390 | 0.76 | KDM4E (0.52) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28455529 | 0.76 | MCL1 (0.60) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11768220 | 0.76 | GPR3 (0.50) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28380848 | 0.76 | GPR3 (0.50) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL6829987 | 0.76 | MAPT (0.52) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28494462 | 0.76 | GPR3 (0.50) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28540289 | 0.76 | GPR3 (0.50) | GPR3MAPTMEN1KMT2ARAB9A | |
| SCHEMBL10745045 | 0.76 | KDM4E (0.52) | GPR3MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493474-A | Condensed-cyclic compound and organic light-emitting element including same | 三星显示有限公司 | 2021-10-12 | — | — | CN | claimed |
| EP-0980386-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 2000-02-23 | — | — | EP | claimed |
| WO-1998056812-A2 | ESTROGEN RECEPTOR CRYSTALS AND LIGANDS | KARO BIO AB (SE) | 1998-12-17 | — | — | WO | claimed |
| CN-120136051-A | Preparation method of difluoro sulfonimide salt solution | 万华化学集团股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-112458001-B | Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof | 上海交通大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114292300-A | Spiro-dihydrobenzothiolline phosphonite monoester compound, preparation and application thereof | 中国科学院上海有机化学研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112458001-A | Bacterial strain capable of degrading polycyclic aromatic hydrocarbon and application thereof | 上海交通大学 | 2021-03-09 | — | — | CN | disclosed |
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6608090-B1 | Post-menopausal osteoporosis, hyperlipidemia, and estrogen dependent cancer, particularly breast and uterine cancer; 2-phenylbenzo(B)thiophene 3-substituted with a 4-aminoethoxy benzoyl group, the amino in piperidine or pyrrolidine ring | ELI LILLY AND COMPANY | 2003-08-19 | — | — | US | disclosed |
| US-6555555-B1 | Inhibitors of interleukin-6 and/or interleukin-12; for example 4,5-dimethyl-1,1-dioxidebenzo(b)thiophene; treating various inflammatory diseases, autoimmune diseases, cancer, osteoporosis | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |
| WO-1996032937-A1 | BENZOTHIOPHENES WITH NOVEL BASIC SIDE CHAINS | ELI LILLY AND COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0738725-A2 | Benzothiophenes with novel basic side chains | ELI LILLY AND COMPANY (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5523416-A | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5512684-A | Process for preparing 3-(4-aminoethoxy-benzoyl) benzo B!-thiophenes | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0693488-A1 | An improved process for preparing 3-(4-aminoethoxy-benzoyl)benzo beta -thiophenes | ELI LILLY AND COMPANY (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0062504-B1 | PROCESS FOR PREPARING 3-(4-AMINOETHOXYBENZOYL)BENZO(B)THIOPHENES | ELI LILLY AND COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4358593-A | BY ACYLATION OF PROTECTED 6-HYDROXY,2-(4-HYDROXYPHENYL) BENZO (B)THIOPHENE USING A FRIEDEL CRAFTS CATALYSTS; HYDROLYSIS | ELI LILLY AND COMPANY (US) | 1982-11-09 | — | — | US | disclosed |
| EP-0062504-A1 | Process for preparing 3-(4-aminoethoxybenzoyl)benzo(b)thiophenes | ELI LILLY AND COMPANY (US) | 1982-10-13 | — | — | EP | disclosed |