Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198047 | 1.00 | TSHR (0.57) | TSHRACP3GAAKMT2AMEN1 | |
| SCHEMBL6691199 | 1.00 | TSHR (0.57) | TSHRACP3GAAKMT2AMEN1 | |
| SCHEMBL11249733 | 0.85 | TSHR (0.46) | TSHRKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL6971362 | 0.80 | ACP3 (0.43) | TSHRACP3KMT2AMEN1TDP1 | |
| SCHEMBL10616896 | 0.80 | ACP3 (0.47) | TSHRACP3KMT2AMEN1MAPT | |
| SCHEMBL8658369 | 0.79 | GAA (0.43) | TSHRACP3GAAKMT2AMEN1 | |
| SCHEMBL15617612 | 0.78 | ESR1 (0.44) | TSHRACP3GAAKMT2AMEN1 | |
| SCHEMBL7262478 | 0.78 | ESR1 (0.59) | TSHRGAACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3496129 | 0.78 | ESR1 (0.59) | TSHRGAACYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3061003 | 0.78 | GAA (0.42) | TSHRACP3GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105296512-A | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC | 2016-02-03 | — | — | CN | disclosed |
| CN-102796750-B | The nucleic acid of nitrilase, encoding nitrilase enzyme, and the method preparing and use them | BASF ENZYMES LLC (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-1849391-B | Nitrilases, nucleic acids encoding nitrilases, and methods of making and using the same | DIVERSA CORP | 2014-06-11 | — | — | CN | disclosed |
| CN-100445375-C | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2008-12-24 | — | — | CN | disclosed |
| CN-1849391-A | Nitrilases, nucleic acids encoding nitrilases, and methods of making and using the same | DIVERSA CORP (US) | 2006-10-18 | — | — | CN | disclosed |
| CN-1268755-C | Process for preparing optical active cyanalcohol through enzyme catalysis alcoholysis reaction resolution | UNIV ZHEJIANG (CN) | 2006-08-09 | — | — | CN | disclosed |
| CN-1753990-A | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2006-03-29 | — | — | CN | disclosed |
| CN-1635129-A | Process for preparing optical active cyanalcohol through enzyme catalysis alcoholysis reaction resolution | UNIV ZHEJIANG (CN) | 2005-07-06 | — | — | CN | disclosed |
| WO-2005037811-A1 | A METHOD FOR THE PRODUCTION OF CHIRAL SUBSTITUTED EPOXIDES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2005-04-28 | — | — | WO | disclosed |