SCHEMBL6971362

SCHEMBL6971362

C#CC(O)c1cccc(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.43
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC2A1 P11166 1/20 0.36
AOC3 Q16853 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
IDO1 P14902 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198047 0.80 TSHR (0.57) ACP3TSHRMEN1KMT2ATDP1
SCHEMBL6503600 0.80 TSHR (0.57) ACP3TSHRMEN1KMT2ATDP1
SCHEMBL10616896 0.80 ACP3 (0.47) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL6691199 0.80 TSHR (0.57) ACP3TSHRMEN1KMT2ATDP1
SCHEMBL7207205 0.79 TSHR (0.38) TSHRIDO1
SCHEMBL27516064 0.78 CYP3A4 (0.44) TSHRTDP1LMNASLC6A2SLC6A4
SCHEMBL6966592 0.78 ADRB1 (0.48) TSHRLMNAADRB2ADRB1ADRB3
SCHEMBL11142983 0.77 PTGS1 (0.44) MEN1KMT2ALMNAADRB3ALDH1A1
SCHEMBL424623 0.76 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL6225449 0.76 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119570160-A High-impact material prepared from recycled polypropylene and preparation method thereof 肇庆市合亚科技有限公司 2025-03-07 CN claimed
CN-119570160-B High-impact material prepared from recycled polypropylene and preparation method thereof 肇庆市合亚科技有限公司 2025-08-22 CN disclosed
CN-119570160-A High-impact material prepared from recycled polypropylene and preparation method thereof 肇庆市合亚科技有限公司 2025-03-07 CN disclosed
CN-119570160-A High-impact material prepared from recycled polypropylene and preparation method thereof 肇庆市合亚科技有限公司 2025-03-07 CN disclosed
EP-1149092-B1 4- AND 5-ALKYNYLOXINDOLES AND 4- AND 5-ALKENYLOXINDOLES HOFFMANN LA ROCHE (CH) 2003-10-29 EP disclosed
US-6605730-B2 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula NIHON BAYER AGROCHEM K.K. (JP) 2003-08-12 US disclosed
US-20030028034-A1 Nematicidal pyrazoles WADA KATSUAKI (JP) 2003-02-06 US disclosed
CN-1331689-A 4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles HOFFMANN LA ROCHE (CH) 2002-01-16 CN disclosed
US-6313310-B1 JUN N-TERMINAL KINASE (JNK) ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS; RHEUMATIC ARTHRITIS AND NEURO-DEGENERATIVE DISEASE TREATMENT HOFFMANN-LA ROCHE INC. 2001-11-06 US disclosed
EP-1149092-A2 4- AND 5-ALKYNYLOXINDOLES AND 4- AND 5-ALKENYLOXINDOLES F. HOFFMANN-LA ROCHE AG (CH) 2001-10-31 EP disclosed
US-6310049-B1 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS NIHON BAYER AGROCHEM K.K. (JP) 2001-10-30 US disclosed
WO-2000035906-A2 4- AND 5-ALKYNYLOXINDOLES AND 4- AND 5-ALKENYLOXINDOLES F. HOFFMANN-LA ROCHE AG (CH) 2000-06-22 WO disclosed
US-4568749-A Certain 5-aryl-2-[(4-aryl)-4-hydroxybutyn-2-yl]-1,2,3,4-γ-carbolines PFIZER INC. (US) 1986-02-04 US disclosed
US-4515768-A STABILIZER AGAINST THERMAL DECOMPOSITION AIRWICK INDUSTRIES, INC. (US) 1985-05-07 US disclosed
US-4510308-A Process for preparing carboline derivatives PFIZER INC. (US) 1985-04-09 US disclosed
EP-0036385-B1 INSECTICIDAL VAPOUR-EMITTING COMPOSITIONS ON THE BASIS OF PYRETHRINOIDS Airwick AG (CH) 1984-05-02 EP disclosed
US-4439415-A PYRETHRINOID AND ABSORPTIVE SUBSTRATE AIRWICK INDUSTRIES, INC. (US) 1984-03-27 US disclosed
EP-0036385-A2 Insecticidal vapour-emitting compositions on the basis of pyrethrinoids Airwick AG (CH) 1981-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028034-A1 Nematicidal pyrazoles CBR3, CBR1, CCR4 ACP3 4172/4885TSHR 1691/4885MEN1 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.