Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495535 | 0.98 | HTT (0.51) | HTTLMNAXBP1HIF1AALDH1A1 | |
| SCHEMBL6427038 | 0.79 | RNASEH1 (0.42) | HTTLMNAXBP1HIF1AALDH1A1 | |
| SCHEMBL6427039 | 0.74 | ERCC1 (0.47) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL710689 | 0.73 | ERCC1 (0.62) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL1410 | 0.73 | ERCC1 (0.62) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL29361703 | 0.73 | ERCC1 (0.62) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL6496871 | 0.72 | KMT2A (0.42) | HTTLMNAXBP1ALDH1A1GAA | |
| Water SCHEMBL4444794 | 0.71 | ERCC1 (0.60) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL1279494 | 0.71 | ERCC1 (0.60) | HTTLMNAXBP1ALDH1A1KMT2A | |
| SCHEMBL2824834 | 0.71 | ERCC1 (0.60) | HTTLMNAXBP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884874-B2 | Process and intermediates | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| US-20040014980-A1 | Such as n-methyl-alanine derivatives; for preparing antibody/maytansinoid complexes | SMITHKLINE BEECHAM PLC | 2004-01-22 | — | — | US | disclosed |
| US-6570024-B2 | N-methyl-L-alanine derivatives derivatives used for preparing cell binding agent/maytansinoid complexes | SMITHKLINE BEECHAM CORPORATION | 2003-05-27 | — | — | US | disclosed |
| US-20020156318-A1 | Process and intermediates | GLAXOSMITHKLINE LLC | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014980-A1 | Such as n-methyl-alanine derivatives; for preparing antibody/maytansinoid complexes | HGFAC, ANPEP, AAAS | HTT 4569/4885LMNA 2177/4885XBP1 3259/4885 |
| US-20020156318-A1 | Process and intermediates | HGFAC, MTAP, SPR | HTT 4568/4885LMNA 703/4885XBP1 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.