Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995693 | 0.82 | CA1 (0.47) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL25435936 | 0.81 | CA1 (0.49) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL12013320 | 0.81 | TSHR (0.52) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9592045 | 0.79 | CA1 (0.50) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL2332155 | 0.77 | TSHR (0.56) | KDM4EALDH1A1CA1CA2CA7 | |
| SCHEMBL9068544 | 0.77 | CA1 (0.51) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL4185937 | 0.77 | CA1 (0.51) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL4185933 | 0.77 | CA1 (0.51) | KDM4EMAPK1CA1CA2CA7 | |
| SCHEMBL28428860 | 0.77 | TSHR (0.56) | KDM4EALDH1A1CA1CA2CA7 | |
| SCHEMBL20281027 | 0.76 | CA1 (0.42) | CA1CA2CA7CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | claimed |
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | disclosed |