Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503990 | 1.00 | CAPN1 (0.45) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6497734 | 0.92 | RAB9A (0.53) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6497738 | 0.92 | RAB9A (0.53) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6506032 | 0.89 | POLB (0.49) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6506038 | 0.89 | POLB (0.49) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6504678 | 0.88 | CAPN1 (0.43) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6504675 | 0.88 | CAPN1 (0.43) | CAPN1RAB9AALDH1A1ENPP2MAPT | |
| SCHEMBL6495356 | 0.88 | ENPP2 (0.46) | CAPN1ENPP2MAPTL3MBTL1ITGAL | |
| SCHEMBL6495354 | 0.88 | ENPP2 (0.46) | CAPN1ENPP2MAPTL3MBTL1ITGAL | |
| SCHEMBL6503636 | 0.87 | ITGAL (0.51) | CAPN1RAB9AALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |