SCHEMBL6504078

SCHEMBL6504078

CC(C)(C)c1cc(C=O)c2c(c1)C(C)(C)c1cc(C(C)(C)C)cc(C=O)c1O2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14245092 0.91 GABBR2 (0.32) GABBR2GABBR1
SCHEMBL12587965 0.84 GABBR2 (0.31) GABBR2GABBR1
SCHEMBL811190 0.77 POLB (0.39) GABBR2GABBR1
SCHEMBL30367805 0.75 GABBR2 (0.37) GABBR2GABBR1
SCHEMBL2142578 0.74 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL14612293 0.74 GABBR2 (0.39) GABBR2GABBR1
SCHEMBL708899 0.74 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL547487 0.74 ALDH1A1 (0.39) GABBR2GABBR1
SCHEMBL21327677 0.74 POLB (0.36) GABBR2GABBR1
SCHEMBL31462832 0.74 POLB (0.36) GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005063730-A1 METHOD FOR THE PRODUCTION OF XANTHENE-4,5-DIOLES SUBSTITUTED IN POSITION 2.7 BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 WO disclosed