Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947574 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL8086154 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL424728 | 0.67 | TSHR (0.73) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL30010382 | 0.67 | ALDH1A1 (0.52) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL348347 | 0.67 | ALDH1A1 (0.52) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL1450324 | 0.66 | ALDH1A1 (0.36) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL2009857 | 0.65 | TSHR (0.52) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL1134715 | 0.65 | ALDH1A1 (0.58) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL7521505 | 0.65 | ALDH1A1 (0.50) | ALDH1A1TDP1HPGDALOX15HSD17B10 | |
| SCHEMBL1134700 | 0.65 | ALDH1A1 (0.58) | ALDH1A1TDP1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |