Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.58 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.49 |
| ▸ | FNTA | P49354 | 4/20 | 0.35 |
| ▸ | FNTB | P49356 | 4/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224035 | 1.00 | ACE2 (0.58) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL6504426 | 0.86 | CYP11B1 (0.61) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL8297235 | 0.86 | CYP11B1 (0.61) | ACE2ACECYP11B1CYP11B2FNTA | |
| Hydrochloric Acid SCHEMBL6504420 | 0.85 | CYP11B1 (0.60) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL8258361 | 0.81 | ACE2 (0.78) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL12517973 | 0.81 | ACE2 (0.57) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL5870455 | 0.81 | ACE2 (0.78) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL12040382 | 0.78 | ACE2 (0.87) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL5869843 | 0.78 | ACE2 (0.87) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL5870265 | 0.78 | ACE2 (0.87) | ACE2ACECYP11B1CYP11B2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319461-A1 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | ORE PHARMACEUTICALS INC. (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110319461-A1 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | ORE PHARMACEUTICALS INC. (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110319461-A1 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | ORE PHARMACEUTICALS INC. (US) | 2011-12-29 | — | — | US | disclosed |
| WO-2011088075-A2 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | ORE PHARMACEUTICALS INC. (US) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011088075-A2 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | ORE PHARMACEUTICALS INC. (US) | 2011-07-21 | — | — | WO | disclosed |
| US-7045532-B2 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | ACE2 2/4885ACE 1/4885CYP11B1 256/4885 |
| US-20110319461-A1 | NOVEL SALTS, POLYMORPHS, AND SYNTHETIC PROCESSES REGARDING IMIDAZOLE DERIVATIVE | IPO4, ACMSD, PPIP5K2 | ACE2 476/4885ACE 382/4885CYP11B1 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.