SCHEMBL417437

SCHEMBL417437

COC(=O)C(C(=O)O)=C(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
CYP19A1 P11511 5/20 0.44
CES1 P23141 3/20 0.42
CES2 O00748 2/20 0.42
PKM P14618 1/20 0.42
SRC P12931 1/20 0.42
KMT2A Q03164 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GLA P06280 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 2/20 0.40
ELANE P08246 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27941250 0.92 TSHR (0.54) TSHRCYP19A1CES1CES2PKM
SCHEMBL12499268 0.89 TSHR (0.50) TSHRCYP19A1CES1CES2PKM
SCHEMBL12499267 0.89 TSHR (0.50) TSHRCYP19A1CES1CES2PKM
SCHEMBL417161 0.84 CA1 (0.53) CYP19A1CES1CES2MAPTKDM4E
SCHEMBL6067697 0.83 CES1 (0.52) TSHRCYP19A1CES1CES2KMT2A
SCHEMBL14868116 0.82 TSHR (0.56) TSHRCYP19A1CES1CES2SRC
SCHEMBL15081529 0.82 TSHR (0.56) TSHRCYP19A1CES1CES2SRC
SCHEMBL14868118 0.82 TSHR (0.56) TSHRCYP19A1CES1CES2SRC
SCHEMBL6504485 0.81 TSHR (0.50) TSHRCES1CES2PKMSRC
SCHEMBL6504482 0.81 TSHR (0.50) TSHRCES1CES2PKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075202-A Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings 弗劳恩霍弗应用研究促进协会 2017-08-18 CN disclosed
US-9232785-B2 Method for reducing sunburn damage in plants BASF SE (DE) 2016-01-12 US disclosed
US-8748347-B2 Method for combating harmful fungi BASF SE (DE) 2014-06-10 US disclosed
US-20120083497-A1 Method for Combating Harmful Fungi BASF SE (DE) 2012-04-05 US disclosed
EP-2418944-A2 METHOD FOR COMBATING HARMFUL FUNGI BASF SE (DE) 2012-02-22 EP disclosed
EP-2413691-A2 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2012-02-08 EP disclosed
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2012-01-26 US disclosed
WO-2010115721-A2 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2010-10-14 WO disclosed
WO-2010115720-A2 METHOD FOR COMBATING HARMFUL FUNGI BASF SE (DE) 2010-10-14 WO disclosed
EP-1487881-A2 SURFACE-ACTIVE PHOTOINITIATORS Ciba SC Holding AG (CH) 2004-12-22 EP disclosed
WO-2002014439-A2 PROCESS FOR PRODUCING COATINGS USING SURFACE-ACTIVE PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-02-21 WO disclosed
WO-2001070869-A2 STERICALLY HINDERED PHENOL ANTIOXIDANT GRANULES HAVING BALANCED HARDNESS ALBEMARLE CORPORATION (US) 2001-09-27 WO disclosed
EP-1124832-A1 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS Ciba SC Holding AG (CH) 2001-08-22 EP disclosed
EP-1088027-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS Ciba SC Holding AG (CH) 2001-04-04 EP disclosed
WO-2000026219-A1 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
WO-1999055772-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-11-04 WO disclosed
US-4798822-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1989-01-17 US disclosed
US-4661594-A PHOTODEGRADATION INHIBITION CIBA-GEIGY CORPORATION (US) 1987-04-28 US disclosed
US-4110305-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-3937711-A POLYMERIC STABILIZERS, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120017503-A1 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS UNG, ERCC5, ERCC4 TSHR 4352/4885CYP19A1 2578/4885CES1 867/4885
US-20120083497-A1 Method for Combating Harmful Fungi BROX, CRY1, GUSB TSHR 4465/4885CYP19A1 2217/4885CES1 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.