Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504486 | 1.00 | PIM1 (0.47) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6530095 | 0.83 | PIM1 (0.45) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6530093 | 0.83 | PIM1 (0.45) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6507809 | 0.83 | PIM1 (0.53) | PIM1PIM2PIM3HPGDMGAM | |
| SCHEMBL6507599 | 0.82 | GSK3B (0.48) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6507602 | 0.82 | GSK3B (0.48) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6505495 | 0.81 | ALDH1A1 (0.46) | POLBGAARAB9ATDP1 | |
| SCHEMBL6511845 | 0.79 | PIM1 (0.50) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6511842 | 0.79 | PIM1 (0.50) | PIM1PIM2PIM3MTORHPGD | |
| SCHEMBL6532952 | 0.77 | PIM1 (0.52) | PIM1PIM2PIM3MTORHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |