Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112330 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6504486 | 0.81 | PIM1 (0.47) | POLBTDP1RAB9AGAA | |
| SCHEMBL6504488 | 0.81 | PIM1 (0.47) | POLBTDP1RAB9AGAA | |
| SCHEMBL6529609 | 0.79 | KMT2A (0.43) | ALDH1A1KMT2AMAPTPOLBLMNA | |
| SCHEMBL6532625 | 0.79 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4118482 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL13690186 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6505839 | 0.72 | PPARG (0.46) | ALDH1A1MEN1KMT2AALOX15MAPT | |
| SCHEMBL4112753 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL4106912 | 0.72 | NPC1 (0.44) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |