Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345918 | 0.83 | CYP1A2 (0.62) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL8080856 | 0.83 | CYP1A2 (0.62) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL8079530 | 0.83 | CYP1A2 (0.62) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL8605995 | 0.82 | MTNR1A (0.61) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL8080874 | 0.82 | MTNR1A (0.61) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL7778584 | 0.82 | MTNR1A (0.61) | CYP1A2MTNR1AMTNR1BEPHX2CA1 | |
| SCHEMBL6075690 | 0.81 | CYP1A2 (0.56) | CYP1A2MTNR1AMTNR1BPOLLEPHX2 | |
| SCHEMBL6498974 | 0.80 | KMT2A (0.47) | EPHX2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10787756 | 0.76 | CYP1A2 (0.52) | CYP1A2POLLEPHX2CA1CA2 | |
| SCHEMBL266254 | 0.74 | KDM4E (0.56) | POLLCA1CA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969724-B2 | Compounds | SMITHKLINE BEECHAM-SPA (GB) | 2005-11-29 | — | — | US | disclosed |
| US-20040024218-A1 | Novel compounds | SMITHKLINE BEECHAM SPA | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024218-A1 | Novel compounds | OXER1, CLIC1, CCR1 | CYP1A2 2010/4885MTNR1A 596/4885MTNR1B 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.