Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DNA2 | P51530 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509909 | 0.83 | KDM4E (0.57) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL5320553 | 0.77 | CSNK2A1 (0.50) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL4718053 | 0.75 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL5794312 | 0.75 | KDM4E (0.44) | CYP1A2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL11022509 | 0.75 | CSNK2A2 (0.55) | CYP1A2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL7002649 | 0.74 | KDM4E (0.43) | CYP1A2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8912217 | 0.74 | KDM4E (0.43) | CYP1A2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL4962609 | 0.73 | CSNK2A2 (0.49) | CYP1A2CYP3A4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7512756 | 0.73 | ALDH1A1 (0.45) | CYP1A2CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL1421988 | 0.72 | CSNK2A2 (0.48) | CYP1A2CYP3A4CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | claimed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |