Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | DNA2 | P51530 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504649 | 0.83 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL30353206 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL8332461 | 0.79 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL7512756 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL1556635 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL7509122 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1HPGDCNR2CSNK2A2 | |
| SCHEMBL17424081 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDCNR2CSNK2A2 | |
| SCHEMBL7017055 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL17424063 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL30353212 | 0.72 | ALDH1A1 (0.97) | KDM4EALDH1A1HPGDCNR2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | claimed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | claimed |
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |