Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793237 | 0.86 | TP53 (0.71) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL11360472 | 0.84 | TP53 (0.69) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL6359764 | 0.83 | ALDH1A1 (0.68) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL13913239 | 0.83 | NAMPT (0.70) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL6503058 | 0.82 | TP53 (0.61) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL4939202 | 0.82 | TP53 (0.66) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL24801410 | 0.82 | TP53 (1.00) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL3207991 | 0.81 | TP53 (0.64) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL6360359 | 0.81 | HDAC3 (0.76) | TP53ALDH1A1HPGDGAAPKM | |
| SCHEMBL4154660 | 0.80 | NPC1 (0.65) | TP53ALDH1A1HPGDGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |