Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495416 | 0.87 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL6497957 | 0.86 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL6496775 | 0.85 | CRHR1 (0.41) | CRHR1DPP4 | |
| SCHEMBL6504823 | 0.80 | CRHR1 (0.38) | CRHR1DPP4 | |
| SCHEMBL6497952 | 0.73 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL6496629 | 0.71 | CRHR1 (0.41) | CRHR1DPP4 | |
| SCHEMBL6495413 | 0.71 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6496771 | 0.69 | CRHR1 (0.40) | CRHR1DPP4 | |
| SCHEMBL6495922 | 0.69 | NPC1 (0.50) | CRHR1 | |
| SCHEMBL6497711 | 0.68 | NPC1 (0.49) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958341-B2 | Pyrazolopyrimidines as CRF antagonists | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-10-25 | — | — | US | disclosed |