Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805684 | 0.77 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1KDRPAK4 | |
| SCHEMBL32686207 | 0.77 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1KDRPAK4 | |
| SCHEMBL32686086 | 0.75 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1KDRPAK4 | |
| SCHEMBL4124241 | 0.69 | KDM4E (0.66) | KDM4EHPGDALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL15309635 | 0.69 | SRC (0.55) | KDRPOLBSMN1; SMN2 | |
| SCHEMBL27084096 | 0.68 | KDM4E (0.41) | CSNK2A1KDM4EALDH1A1SHMT2SMN1; SMN2 | |
| SCHEMBL1098501 | 0.68 | HPGD (0.54) | CSNK2A2CSNK2BCSNK2A1KDRPAK4 | |
| SCHEMBL6507663 | 0.68 | GRIN3B (0.49) | KDRKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL843921 | 0.67 | KDM4E (0.54) | CSNK2A2CSNK2BCSNK2A1KDRKDM4E | |
| Hydrochloric Acid SCHEMBL26117682 | 0.67 | KDM4E (0.40) | CSNK2A1KDM4EALDH1A1SHMT2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081960-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |