Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.41 |
| ▸ | PPARA | Q07869 | 12/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497309 | 0.86 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL6502621 | 0.83 | PPARG (0.41) | PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6504833 | 0.82 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL6498702 | 0.81 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL5552673 | 0.80 | PPARG (0.37) | PPARGPPARAMMP1PPARDL3MBTL1 | |
| SCHEMBL5549053 | 0.79 | PPARG (0.35) | PPARGPPARAMMP1PPARDL3MBTL1 | |
| SCHEMBL6498647 | 0.77 | PPARG (0.37) | PPARGPPARAPPARDTPH1 | |
| SCHEMBL5549704 | 0.76 | PPARG (0.38) | PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL5553471 | 0.76 | PPARG (0.35) | PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6497349 | 0.75 | OPRK1 (0.40) | PPARGPPARAMMP1PPARDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |