Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099922 | 0.84 | PPARG (0.59) | PPARGL3MBTL1LMNAKDM4EMEN1 | |
| SCHEMBL458396 | 0.80 | MMP8 (0.37) | PPARGLMNAMAPTPPARAACE | |
| SCHEMBL15510768 | 0.80 | MMP8 (0.40) | KDM4EMAPTKMT2APPARAPPARD | |
| SCHEMBL7708014 | 0.80 | CYP4F2 (0.47) | KDM4EKMT2AMAOBALOX5MME | |
| SCHEMBL7620591 | 0.78 | FFAR1 (0.50) | PPARGPPARAFFAR1 | |
| SCHEMBL6504864 | 0.78 | MMP8 (0.63) | PPARGL3MBTL1LMNAKDM4EMEN1 | |
| SCHEMBL7617574 | 0.76 | NPSR1 (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL7622718 | 0.76 | LTB4R (0.44) | KDM4EMAOBALOX5MMEACE | |
| SCHEMBL1497878 | 0.76 | FFAR1 (0.44) | PPARGL3MBTL1LMNAKDM4EMEN1 | |
| SCHEMBL5326113 | 0.76 | PPARG (0.59) | PPARGL3MBTL1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |