SCHEMBL6504893

SCHEMBL6504893

Nc1cnc(NS(=O)(=O)c2ccccc2)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.54
CA12 O43570 1/20 0.54
CA2 P00918 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
ATM Q13315 1/20 0.49
KEAP1 Q14145 2/20 0.47
ALDH1A1 P00352 4/20 0.47
LMNA P02545 3/20 0.47
GAA P10253 2/20 0.47
CCNE2 O96020 1/20 0.46
CCNE1 P24864 1/20 0.46
CDK2 P24941 1/20 0.46
KDM4E B2RXH2 2/20 0.46
IL1RN P18510 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14921838 0.81 ALDH1A1 (0.54) CA1CA12CA2CA3CA6
SCHEMBL1094463 0.81 CA1 (0.50) CA1CA12CA2CA3CA6
SCHEMBL1094876 0.81 SCN9A (0.52) CA1CA12CA2CA3CA6
SCHEMBL25349874 0.76 LMNA (0.66) CA1CA12CA2CA3CA6
SCHEMBL2783467 0.76 MEN1 (0.58) CA1CA12CA2CA3CA6
SCHEMBL27875742 0.75 CA1 (0.68) CA1CA12CA2CA3CA6
SCHEMBL6501402 0.74 PIK3CB (0.39) CA1CA12CA2CA5ACA9
SCHEMBL2177779 0.72 LMNA (0.62) CA1CA12CA2CA3CA6
SCHEMBL17868333 0.71 PIK3CB (0.67) CA1CA12CA2CA9KEAP1
SCHEMBL25352069 0.71 GAA (0.69) CA1CA12CA2CA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005014591-A1 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2005-02-17 WO disclosed