Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927905 | 0.95 | GRIN1 (0.46) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| SCHEMBL1925260 | 0.95 | GRIN1 (0.46) | GRIN1GRIN2BPTGIRPTGDRPDE4B | |
| SCHEMBL1925391 | 0.91 | GRIN1 (0.43) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| SCHEMBL1925124 | 0.86 | GRIN1 (0.44) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| SCHEMBL6504986 | 0.86 | PTGIR (0.38) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| SCHEMBL1925070 | 0.85 | GRIN1 (0.46) | GRIN1GRIN2BPTGIRPTGDRPDE4B | |
| SCHEMBL1924763 | 0.85 | GRIN1 (0.42) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| Hydrochloric Acid SCHEMBL1925303 | 0.84 | GRIN1 (0.41) | GRIN1GRIN2BPTGIRPTGDRROCK2 | |
| Hydrochloric Acid SCHEMBL1927908 | 0.84 | GRIN1 (0.46) | GRIN1GRIN2BPTGIRPTGDRPDE4B | |
| SCHEMBL1925192 | 0.83 | GRIN1 (0.47) | GRIN1GRIN2BPTGIRPTGDRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869954-B2 | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| US-20030119838-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119838-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | IL1A, IL1B, IL1R1 | GRIN1 519/4885GRIN2B 2978/4885PTGIR 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.