Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 12/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498341 | 0.88 | LMNA (0.38) | TP53PPARGPPARAPPARDMAPT | |
| SCHEMBL6498815 | 0.88 | PPARG (0.37) | TP53PPARGPPARAPPARDMAPT | |
| SCHEMBL6494217 | 0.87 | S1PR3 (0.36) | TP53PPARGPPARAPPARDMAPT | |
| SCHEMBL6494327 | 0.86 | EPHX2 (0.37) | TP53PPARGPPARAPPARDMAPT | |
| SCHEMBL6504030 | 0.86 | PPARG (0.37) | PPARGPPARAPPARDACACB | |
| SCHEMBL6504955 | 0.86 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6507629 | 0.84 | PPARA (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6502816 | 0.84 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6502543 | 0.84 | LMNA (0.38) | TP53PPARGPPARAPPARDMAPT | |
| SCHEMBL6495940 | 0.84 | PPARG (0.38) | PPARGPPARAPPARDACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |