Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118818 | 0.85 | PTPN1 (0.39) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL6505258 | 0.83 | MAPT (0.35) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4131053 | 0.83 | SMN1; SMN2 (0.43) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4121844 | 0.82 | MAPT (0.38) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4131424 | 0.80 | MAPT (0.37) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4131737 | 0.80 | L3MBTL1 (0.41) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4119302 | 0.80 | LIPG (0.42) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4132094 | 0.80 | KDM4E (0.36) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4132097 | 0.80 | KDM4E (0.36) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL4124207 | 0.79 | MAPT (0.39) | MAPTKDM4EALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081960-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |