Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144164 | 0.66 | SMN1; SMN2 (0.52) | MEN1KMT2AGAADRD2DRD3 | |
| SCHEMBL7617293 | 0.65 | PARP1 (0.46) | MEN1KMT2AGAADRD2DRD4 | |
| SCHEMBL10084514 | 0.64 | HRH3 (0.64) | HRH3MAOB | |
| SCHEMBL3072602 | 0.63 | PARP1 (0.53) | GAADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL17702656 | 0.62 | FGFR1 (0.45) | MEN1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL17702655 | 0.62 | LMNA (0.52) | MEN1KMT2ATP53LMNARAB9A | |
| SCHEMBL10879465 | 0.62 | CYP3A4 (0.57) | SMN1; SMN2ACACBHRH3MAOBCYP3A4 | |
| SCHEMBL1133575 | 0.62 | HRH3 (0.61) | HRH3MAOB | |
| SCHEMBL8262967 | 0.61 | ALDH1A1 (0.47) | MEN1KMT2AGAADRD2DRD4 | |
| SCHEMBL9593021 | 0.61 | HRH3 (0.57) | MEN1KMT2ATP53LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |