Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FHIT | P49789 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852589 | 0.86 | NPSR1 (0.47) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL10426601 | 0.83 | GAA (0.50) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL4968092 | 0.83 | ALDH1A1 (0.47) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL5731466 | 0.83 | ALDH1A1 (0.47) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL1973691 | 0.83 | ALDH1A1 (0.55) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL16705221 | 0.83 | ALDH1A1 (0.47) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL20503315 | 0.82 | NPSR1 (0.50) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL28959134 | 0.82 | MEN1 (0.53) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL2616832 | 0.81 | GAA (0.58) | GAAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL16437812 | 0.81 | ALDH1A1 (0.54) | GAAALDH1A1CYP1A2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |