Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849586 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL18792316 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL10350633 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL18792315 | 0.84 | ALDH1A1 (0.43) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL27832378 | 0.83 | KMT2A (0.33) | ALDH1A1CYP1A2GAANPC1MAPK1 | |
| SCHEMBL28397631 | 0.83 | MEN1 (0.42) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL9861374 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL6505364 | 0.83 | GAA (0.55) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL10317272 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A2GAAMAPTNPC1 | |
| SCHEMBL595444 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620433-B1 | SUBSTITUTED AMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2015-05-13 | — | — | EP | disclosed |