Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.38 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6504351 | 0.98 | TSHR (0.50) | TSHRNAAALTA4HCHRM2CHRM1 | |
| SCHEMBL10503182 | 0.90 | TSHR (0.47) | TSHRNAAALTA4HCHRM2CHRM1 | |
| SCHEMBL12013320 | 0.83 | TSHR (0.52) | TSHRNAAALYPLA1LYPLA2ALDH1A1 | |
| SCHEMBL11465304 | 0.82 | TSHR (0.54) | TSHRNAAALTA4HPPARGALDH1A1 | |
| SCHEMBL6267162 | 0.81 | TSHR (0.58) | TSHRNAAALTA4HALDH1A1LMNA | |
| SCHEMBL5726273 | 0.81 | TSHR (0.58) | TSHRNAAALTA4HALDH1A1LMNA | |
| SCHEMBL11110263 | 0.79 | TSHR (0.47) | TSHRNAAALTA4HPPARGALDH1A1 | |
| SCHEMBL4608747 | 0.79 | TSHR (0.74) | TSHRNAAALTA4HLMNAHTT | |
| SCHEMBL9505432 | 0.79 | TSHR (0.74) | TSHRNAAALTA4HLMNAHTT | |
| SCHEMBL26189828 | 0.79 | TSHR (0.74) | TSHRNAAALTA4HLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | claimed |
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005028457-A1 | PREPARATION OF QUETIAPINE | FERMION OY (FI) | 2005-03-31 | — | — | WO | disclosed |