Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465304 | 0.93 | TSHR (0.54) | TSHROPRM1OPRD1OPRK1BCHE | |
| SCHEMBL6505489 | 0.90 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL11110263 | 0.90 | TSHR (0.47) | TSHROPRM1OPRD1OPRK1BCHE | |
| Hydrochloric Acid SCHEMBL6504351 | 0.88 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL10622030 | 0.85 | HTT (0.49) | TSHROPRM1OPRD1OPRK1BCHE | |
| SCHEMBL373667 | 0.83 | OPRM1 (0.48) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL2248674 | 0.83 | TSHR (0.47) | TSHRBCHEHRH3TDP1PPARG | |
| SCHEMBL479112 | 0.81 | OPRM1 (0.47) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL144177 | 0.81 | OPRM1 (0.50) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| Bromide SCHEMBL8961491 | 0.81 | OPRM1 (0.47) | TSHROPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172632-B1 | Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0114002-B1 | BENZOTHIOPYRANO(4,3,2,-CD)INDAZOLES, THEIR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4604390-A | FUNGICIDES, ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0172632-A1 | Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4472584-A | HYPOTENSIVE AGENTS | USV PHARMACEUTICAL CORPORATION (US) | 1984-09-18 | — | — | US | disclosed |