Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503182 | 0.90 | TSHR (0.47) | TSHRPPARGPPARABCHEOPRM1 | |
| SCHEMBL11465304 | 0.89 | TSHR (0.54) | TSHRPPARGPPARABCHEOPRM1 | |
| SCHEMBL2248674 | 0.83 | TSHR (0.47) | TSHRPPARGPPARABCHENAAA | |
| SCHEMBL10622030 | 0.81 | HTT (0.49) | TSHRPPARGPPARABCHEOPRM1 | |
| SCHEMBL6505489 | 0.79 | TSHR (0.52) | TSHRPPARGNAAAL3MBTL1LTA4H | |
| SCHEMBL10502279 | 0.79 | PPARG (0.56) | TSHRPPARGPPARAL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6504351 | 0.78 | TSHR (0.50) | TSHRPPARGNAAALTA4HALDH1A1 | |
| SCHEMBL9422360 | 0.78 | TSHR (0.41) | TSHRPPARGPPARABCHEOPRM1 | |
| SCHEMBL2795989 | 0.77 | OPRM1 (0.44) | TSHROPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL12918861 | 0.77 | TSHR (0.45) | TSHROPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114002-A2 | Benzothiopyrano(4,3,2,-cd)indazoles, their pharmaceutical compositions and methods for their production | WARNER-LAMBERT COMPANY (US) | 1984-07-25 | — | — | EP | disclosed |