Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298679 | 1.00 | NPC1 (0.47) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL30714783 | 0.88 | RAB9A (0.46) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL1627274 | 0.83 | NPC1 (0.53) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL5288034 | 0.83 | NPC1 (0.53) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL11099516 | 0.83 | NPC1 (0.53) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL7926603 | 0.79 | PPARG (0.50) | PPARG | |
| SCHEMBL5775890 | 0.76 | NPC1 (0.51) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL5624696 | 0.76 | MAPT (0.54) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL6495999 | 0.75 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL7909117 | 0.75 | NPC1 (0.58) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |