Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.55 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.55 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498023 | 0.90 | TNNC1 (0.57) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8499522 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL6529404 | 0.88 | S1PR1 (0.59) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8500291 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8497060 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8498534 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8497058 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8495964 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8496561 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 | |
| SCHEMBL8496781 | 0.88 | TNNC1 (0.60) | S1PR1TNNC1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |