Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.59 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.56 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904016 | 0.88 | S1PR1 (0.58) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL6505535 | 0.88 | S1PR1 (0.55) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| Hydrochloric Acid SCHEMBL8497906 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL16202272 | 0.85 | S1PR1 (0.59) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL565320 | 0.84 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL6528287 | 0.84 | S1PR1 (0.68) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| Hydrochloric Acid SCHEMBL6528090 | 0.82 | S1PR1 (0.69) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL11927165 | 0.81 | S1PR1 (0.55) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL5564657 | 0.81 | S1PR1 (0.55) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL6529683 | 0.81 | HTT (0.49) | S1PR1S1PR3FFAR1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |