Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | UBE2I | P63279 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496963 | 0.90 | TP53 (0.39) | PPARGPPARAUBE2ICACNA1BAPBA1 | |
| SCHEMBL6496468 | 0.87 | MAPT (0.38) | PPARGPPARAUBE2ICACNA1BAPBA1 | |
| SCHEMBL6504909 | 0.87 | S1PR3 (0.38) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6502543 | 0.87 | LMNA (0.38) | PPARGPPARAUBE2ICACNA1BAPBA1 | |
| SCHEMBL6505766 | 0.85 | PPARG (0.39) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6503457 | 0.85 | PDE4A (0.42) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6503035 | 0.85 | S1PR3 (0.36) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6502859 | 0.85 | S1PR3 (0.36) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6494217 | 0.85 | S1PR3 (0.36) | S1PR3HRH3PPARGPPARAEPHX2 | |
| SCHEMBL6503062 | 0.84 | PDE4A (0.40) | S1PR3HRH3PPARGPPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |