Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | UBE2I | P63279 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496468 | 0.92 | MAPT (0.38) | TP53HPGDSMN1; SMN2UBE2ICACNA1B | |
| SCHEMBL6502543 | 0.92 | LMNA (0.38) | TP53HPGDSMN1; SMN2UBE2ICACNA1B | |
| SCHEMBL6505538 | 0.90 | S1PR3 (0.38) | UBE2ICACNA1BAPBA1SAE1UBA2 | |
| SCHEMBL6502348 | 0.85 | EPHX2 (0.36) | TP53EPHX2NR1H4ALDH1A1MAPT | |
| SCHEMBL7685465 | 0.84 | EPHX2 (0.36) | TP53HPGDSMN1; SMN2EPHX2NR1H4 | |
| SCHEMBL6505285 | 0.84 | PPARA (0.43) | EPHX2NR1H4PPARAPPARGPPARD | |
| SCHEMBL6494327 | 0.84 | EPHX2 (0.37) | TP53HPGDEPHX2NR1H4ALDH1A1 | |
| SCHEMBL6502157 | 0.83 | NR1H4 (0.37) | TP53HPGDSMN1; SMN2EPHX2NR1H4 | |
| SCHEMBL6504440 | 0.82 | EPHX2 (0.36) | EPHX2NR1H4ALDH1A1PPARAPPARG | |
| SCHEMBL6503712 | 0.82 | PPARA (0.50) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |