Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977475 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL6584154 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL10391474 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL7056947 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL295741 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL23617411 | 0.83 | KMT2A (0.47) | LMNAKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL27658015 | 0.82 | MEN1 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9559495 | 0.81 | KMT2A (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7635592 | 0.77 | CASR (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11041623 | 0.76 | LMNA (0.50) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |