Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683194 | 1.00 | PPARA (0.45) | PPARAPPARDPPARGMEN1ALDH1A1 | |
| SCHEMBL6060873 | 0.84 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6060870 | 0.84 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6496306 | 0.83 | ADRB2 (0.45) | PPARAPPARDPPARGHTTMMP1 | |
| SCHEMBL6506017 | 0.82 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6504226 | 0.81 | PPARA (0.44) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6504220 | 0.81 | PPARA (0.44) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6504240 | 0.81 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL6496012 | 0.80 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL4341727 | 0.79 | PTGDR2 (0.44) | PPARAPPARDPPARGMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |