Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506033 | 1.00 | USP30 (0.55) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL13606446 | 1.00 | USP30 (0.55) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL1055082 | 0.92 | USP30 (0.62) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL853539 | 0.92 | USP30 (0.62) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL13177349 | 0.92 | USP30 (0.62) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL14037432 | 0.92 | USP30 (0.62) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL853540 | 0.92 | USP30 (0.62) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL15312509 | 0.90 | USP30 (0.51) | USP30FUCA1L3MBTL1ATMALDH1A1 | |
| SCHEMBL4862883 | 0.88 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL21593409 | 0.88 | L3MBTL1 (0.57) | USP30L3MBTL1ATMALDH1A1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033076-A1 | METHOD FOR PREPARING 3-HYDROXY-4-HYDROXYMETHYL-PYRROLIDINE COMPOUNDS | INDUSTRIAL RESEARCH LIMITED (NZ) | 2005-04-14 | — | — | WO | disclosed |