Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28818373 | 0.99 | L3MBTL1 (0.56) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL5751253 | 0.90 | MAPT (0.53) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL21593409 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL3548161 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL21593413 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL29198358 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL3551153 | 0.90 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL5752863 | 0.89 | L3MBTL1 (0.48) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| Hydrochloric Acid SCHEMBL28818356 | 0.89 | L3MBTL1 (0.56) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL6506401 | 0.88 | USP30 (0.55) | L3MBTL1ATMALDH1A1CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509438-B2 | Pyrazole derivative | APTABIO THERAPEUTICS INC. (KR) | 2025-12-30 | — | — | US | disclosed |
| US-20230067461-A1 | NOVEL PYRAZOLE DERIVATIVE | APTABIO THERAPEUTICS INC. (KR) | 2023-03-02 | — | — | US | disclosed |
| EP-4105206-A1 | NOVEL PYRAZOLE DERIVATIVE | Aptabio Therapeutics Inc. (KR) | 2022-12-21 | — | — | EP | disclosed |
| CN-114945561-A | Novel pyrazole derivatives | 阿普塔生物治疗公司 | 2022-08-26 | — | — | CN | disclosed |
| WO-2021145655-A1 | NOVEL PYRAZOLE DERIVATIVE | 압타바이오 주식회사 | 2021-07-22 | — | — | WO | disclosed |
| CN-112778301-A | Tetrahydropyridopyrimidine inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-2920149-B1 | 3-AMINOCYCLOALKYL COMPOUNDS AS ROR-GAMMA-T INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME (US) | 2019-03-20 | — | — | EP | disclosed |
| EP-2920149-B1 | 3-AMINOCYCLOALKYL COMPOUNDS AS ROR-GAMMA-T INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10227329-B2 | Compounds useful for treating disorders related to RET | BLUEPRINT MEDICINES CORPORATION (US) | 2019-03-12 | — | — | US | disclosed |
| WO-2014028600-A2 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | disclosed |
| WO-2014028600-A2 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | disclosed |
| CN-101434596-A | Novel azaheterocyclic amides useful for treating pain | ABBOTT LAB (US) | 2009-05-20 | — | — | CN | disclosed |
| US-20080153809-A1 | NOVEL AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | US | disclosed |
| US-7348343-B2 | Amides useful for treating pain | ABBOTT LABORATORIES INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070010557-A1 | Novel amides useful for treating pain | ABBVIE INC. | 2007-01-11 | — | — | US | disclosed |
| US-7129235-B2 | Amides useful for treating pain | ABBOTT LABORATORIES (US) | 2006-10-31 | — | — | US | disclosed |
| CN-1849315-A | Novel nitrogen-containing heterocyclic amides for the treatment of pain | ABBOTT LAB (US) | 2006-10-18 | — | — | CN | disclosed |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | ABBVIE INC. | 2005-04-14 | — | — | US | disclosed |
| US-20050009841-A1 | Novel amides useful for treating pain | ABBOTT LABORATORIES | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227329-B2 | Compounds useful for treating disorders related to RET | RET, EYA2, HRAS | L3MBTL1 602/4885ATM 2970/4885ALDH1A1 2131/4885 |
| US-20050009841-A1 | Novel amides useful for treating pain | OPRL1, OPRK1, FAAH2 | L3MBTL1 4022/4885ATM 4646/4885ALDH1A1 519/4885 |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | TRPV1, OPRL1, TRPV6 | L3MBTL1 1917/4885ATM 4852/4885ALDH1A1 843/4885 |
| US-12509438-B2 | Pyrazole derivative | CBR3, NR3C2, NR3C1 | L3MBTL1 2730/4885ATM 3988/4885ALDH1A1 769/4885 |
| US-20230067461-A1 | NOVEL PYRAZOLE DERIVATIVE | CYP3A5, CYP3A7, CYP3A4 | L3MBTL1 4824/4885ATM 3142/4885ALDH1A1 507/4885 |
| US-20070010557-A1 | Novel amides useful for treating pain | OPRL1, PDE6B, PDE6G | L3MBTL1 849/4885ATM 4143/4885ALDH1A1 364/4885 |
| US-20080153809-A1 | NOVEL AMIDES USEFUL FOR TREATING PAIN | OPRL1, OPRK1, OPRD1 | L3MBTL1 1377/4885ATM 4635/4885ALDH1A1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.