SCHEMBL650649

SCHEMBL650649

CCCOC(=O)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
MAPK1 P28482 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
PAM P19021 1/20 0.61
LMNA P02545 1/20 0.56
TSHR P16473 1/20 0.55
TDP1 Q9NUW8 1/20 0.53
KMT2A Q03164 1/20 0.53
ALOX5 P09917 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
AKR1B1 P15121 1/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ADRB2 P07550 1/20 0.48
ADRB1 P08588 1/20 0.48
ADRB3 P13945 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27500595 0.96 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL17789176 0.90 ALDH1A1 (0.55) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL456516 0.89 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1PAMTSHR
SCHEMBL11685649 0.89 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL28250124 0.89 TSHR (0.53) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL1434644 0.88 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL27672935 0.87 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1PAMTSHR
Hydrochloric Acid SCHEMBL27576461 0.87 L3MBTL1 (0.58) ALDH1A1MAPK1L3MBTL1PAMTSHR
SCHEMBL13415626 0.87 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1PAMLMNA
SCHEMBL539127 0.87 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1PAMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080502-A Furfuryl alcohol copolymer coated ammonium polyphosphate and application thereof in preparation of flame-retardant composite material 2026-05-26 CN claimed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
CN-120118497-A Polymaleimide microsphere/polypropylene carbonate composite material and preparation method thereof 河南大学 2025-06-10 CN claimed
CN-119751732-A Synthesis method of halogenated olefin-functional monomer copolymer 江苏扬农化工集团有限公司 2025-04-04 CN claimed
CN-119708315-A Method for synthesizing olefin functional polymer with assistance of microwave irradiation 江苏扬农化工集团有限公司 2025-03-28 CN claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP claimed
CN-117651462-A Method for preparing film, photoelectric device and electronic equipment TCL科技集团股份有限公司 2024-03-05 CN claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
CN-1893910-A Cyclic siloxane compositions for active ingredient release GEN ELECTRIC (US) 2007-01-10 CN claimed
EP-1716159-A2 CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS General Electronic Company (US) 2006-11-02 EP claimed
EP-1697386-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES General Electric Company A Corporation of the State of New York (US) 2006-09-06 EP claimed
WO-2005066187-A1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
WO-2005066186-A2 CYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS GENERAL ELECTRIC COMPANY (US) 2005-07-21 WO claimed
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-20050136021-A1 Active-releasing cyclic siloxanes MOMENTIVE PERFORMANCE MATERIALS INC. 2005-06-23 US claimed
US-4212989-A ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-07-15 US claimed
US-4113362-A LIGHT VALVE, LIGHT VALVE SUSPENSION MATERIALS AND SUSPENSION THEREFOR RESEARCH FRONTIERS INCORPORATED (US) 1978-09-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136022-A1 Cyclic siloxane compositions for the release of active ingredients F9, RPL39, ECPAS ALDH1A1 44/4885MAPK1 4256/4885L3MBTL1 1536/4885
US-20050136021-A1 Active-releasing cyclic siloxanes F9, RPL39, ALDH16A1 ALDH1A1 57/4885MAPK1 4332/4885L3MBTL1 1554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.