Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16816111 | 0.82 | CA1 (0.45) | LMNAPOLBRXFP1BRD9TRPV1 | |
| SCHEMBL8953420 | 0.82 | CA1 (0.45) | LMNAPOLBRXFP1BRD9TRPV1 | |
| SCHEMBL29509673 | 0.81 | LMNA (0.46) | LMNAPOLBRXFP1CNR2BRD9 | |
| SCHEMBL5785123 | 0.81 | LMNA (0.46) | LMNAPOLBRXFP1CNR2BRD9 | |
| SCHEMBL5614473 | 0.80 | LMNA (0.45) | LMNAPOLBRXFP1CNR2BRD9 | |
| SCHEMBL17680239 | 0.79 | CYP2C19 (0.54) | POLBBRD4ALDH1A1HPGDRAB9A | |
| SCHEMBL2880191 | 0.78 | LMNA (0.54) | LMNAPOLBRXFP1CNR2BRD9 | |
| SCHEMBL29991524 | 0.76 | POLB (0.50) | LMNAPOLBRXFP1ALDH1A1 | |
| SCHEMBL13980716 | 0.76 | POLB (0.50) | LMNAPOLBRXFP1ALDH1A1 | |
| SCHEMBL21251514 | 0.75 | SMN1; SMN2 (0.47) | LMNAPOLBRXFP1CNR2BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087776-A1 | DIASTEREOSELECTIVE EPOXIDATION OF ALLYLICALLY SUBSTITUTED ALKENES USING METALLOPORPHYRIN CATALYSTS | THE UNIVERSITY OF HONG KONG (CN) | 2005-09-22 | — | — | WO | disclosed |
| EP-0172347-A2 | Renin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-02-26 | — | — | EP | disclosed |