Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509096 | 0.81 | PPARG (0.50) | PPARGFFAR1PPARAMAPT | |
| SCHEMBL6527097 | 0.79 | LMNA (0.47) | PTPN1CA2ALDH1A1NPSR1MAPT | |
| SCHEMBL6508321 | 0.78 | PTPN1 (0.47) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6529203 | 0.77 | PPARG (0.44) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6530507 | 0.76 | PTPN1 (0.46) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL4778234 | 0.75 | KDM4E (0.53) | PTPN1ALDH1A1NPSR1PPARGFFAR1 | |
| SCHEMBL6513142 | 0.75 | PTPN1 (0.47) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6516282 | 0.75 | PTPN1 (0.45) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL8182679 | 0.74 | PTPN1 (0.79) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6505878 | 0.74 | ESRRA (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058813-A2 | THIODIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND DIAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-30 | — | — | WO | claimed |
| WO-2005058813-A2 | THIODIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND DIAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-30 | — | — | WO | disclosed |