Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | FPR1 | P21462 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692850 | 0.94 | MAPT (0.80) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3952425 | 0.94 | MAPT (0.80) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4683758 | 0.92 | KDM4E (1.00) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2184783 | 0.84 | KDM4E (0.62) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL16120877 | 0.83 | KDM4E (0.68) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2181512 | 0.83 | MAPT (0.61) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2182899 | 0.83 | KDM4E (0.74) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2180371 | 0.82 | KDM4E (0.60) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6923618 | 0.82 | KDM4E (0.64) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10472254 | 0.81 | KDM4E (0.72) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143588-A1 | Production of isoflavone derivatives | NOVOGEN RESEARCH PTY LTD. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143588-A1 | Production of isoflavone derivatives | CYP51A1, EGLN2, EGLN3 | MAPT 3761/4885KDM4E 1806/4885ALDH1A1 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.