Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.43 |
| ▸ | PPARA | Q07869 | 14/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532483 | 1.00 | PPARG (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6533954 | 0.93 | PPARG (0.49) | PPARGPPARAALOX5 | |
| SCHEMBL6532459 | 0.93 | PPARG (0.49) | PPARGPPARAALOX5 | |
| SCHEMBL6532843 | 0.85 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6532379 | 0.80 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6532376 | 0.80 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6532104 | 0.78 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6532682 | 0.78 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6532687 | 0.78 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 | |
| SCHEMBL6532098 | 0.78 | LTA4H (0.43) | PPARGPPARALTA4HPPARDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |