SCHEMBL6506626

SCHEMBL6506626

CC(C)(C)OC(=O)NCC1(C2CCCCC2)CCNCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.45
HCRTR2 O43614 1/20 0.38
GAA P10253 2/20 0.37
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
GFER P55789 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
BTK Q06187 1/20 0.33
PADI1 Q9ULC6 1/20 0.32
PADI4 Q9UM07 1/20 0.32
P2RX7 Q99572 1/20 0.32
FPR3 P25089 1/20 0.32
FPR2 P25090 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23070850 0.93 HCRTR2 (0.40) EPHX1HCRTR2GAACTSSCTSK
SCHEMBL7098423 0.80 EPHX1 (0.40) EPHX1HCRTR2GAACTSSCTSK
SCHEMBL14432052 0.78 EPHX1 (0.39) EPHX1HCRTR2GAACTSSCTSK
Hydrochloric Acid SCHEMBL22389973 0.77 EPHX1 (0.38) EPHX1HCRTR2GAACTSSCTSK
SCHEMBL6507225 0.77 GAA (0.40) EPHX1GAACTSSCTSKMEN1
SCHEMBL2348782 0.76 HCRTR2 (0.40) EPHX1HCRTR2GAAMEN1KMT2A
SCHEMBL12070264 0.76 HCRTR2 (0.43) EPHX1HCRTR2GAAMEN1KMT2A
SCHEMBL8383866 0.75 HCRTR2 (0.38) EPHX1HCRTR2GAACTSSCTSK
SCHEMBL1709941 0.75 HCRTR2 (0.38) EPHX1HCRTR2GAACTSSCTSK
Hydrochloric Acid SCHEMBL22495697 0.75 HCRTR2 (0.42) EPHX1HCRTR2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005047253-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed