Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10839310 | 0.98 | NOTUM (0.40) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL30338444 | 0.81 | APEX1 (0.34) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL28020004 | 0.78 | NR3C2 (0.39) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8342110 | 0.76 | MAPT (0.43) | KDM4EALDH1A1L3MBTL1RIPK1 | |
| SCHEMBL30410306 | 0.76 | MAPT (0.43) | KDM4EALDH1A1L3MBTL1RIPK1 | |
| SCHEMBL10555531 | 0.74 | MAPK14 (0.60) | NR3C2MAPK14 | |
| SCHEMBL23142218 | 0.74 | ALDH1A1 (0.46) | ALDH1A1NR3C2 | |
| SCHEMBL10446532 | 0.73 | HTR2C (0.40) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL3644639 | 0.72 | FABP6 (0.41) | KDM4EALDH1A1L3MBTL1RIPK1 | |
| SCHEMBL30665414 | 0.72 | FABP6 (0.41) | KDM4EALDH1A1L3MBTL1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |